EPCR–PAR1 biased signalling regulates perfusion recovery and neovascularization in peripheral ischemia
JCI Insight · 2022 · confocal image selected for the cover
View article →Publications
My published research in endothelial biology, thrombosis and cardiovascular disease — 36 peer-reviewed papers since 2010, 10 of them as first author, two with my confocal image on the cover of Circulation Research and JCI Insight.
JCI Insight · 2022 · confocal image selected for the cover
View article →Circulation Research · 2019 · confocal image selected for the cover (2020 issue)
View article →Research and Practice in Thrombosis and Haemostasis · 2026
View article →Pulmonary Circulation · 2026
View article →Visualization of new vessel formation during venous thrombus organization using genetic fate mapping First author
Bochenek ML, Noorali JD, Aderajew A, … Schäfer K · Research and Practice in Thrombosis and Haemostasis · 10.1016/j.rpth.2026.106842
Protocol for inducing deep vein thrombosis in C57BL/6J mice using the inferior vena cava stenosis model
Damara A, Canon S, Bochenek ML, Schäfer K, Shahneh F · STAR Protocols · 10.1016/j.xpro.2026.104665
Loss of erythrocyte arginase-1 impairs vasorelaxation due to endothelial GSNOR overexpression and denitrosylation of G protein subunits
Gogiraju R, Sun B, Bochenek ML, … Schäfer K · Redox Biology · 10.1016/j.redox.2026.104201
Chronic Erythrocyte NO Production Accelerates Atherosclerosis by Increasing SMC De Novo Lipogenesis
Sun B, Gogiraju R, Greulich F, … Bochenek ML … Schäfer K · Circulation Research · 10.1161/CIRCRESAHA.125.327866
Transmembrane Protein 100 Expression on Endothelial Cells Vascularizing Thrombi in Chronic Thromboembolic Pulmonary Hypertension Modulates TGFβ1-ALK1 Signaling During Angiogenesis First author
Bochenek ML, Ghasemi I, Wiedenroth CB, … Schäfer K · Pulmonary Circulation · 10.1002/pul2.70253
Side-by-Side Comparison of Culture Media Uncovers Phenotypic and Functional Differences in Primary Mouse Aortic Mural Cells
Ghasemi I, Gogiraju R, Khraisat S, … Bochenek ML … Schäfer K · Cells · 10.3390/cells14120927
Myeloid cell-derived interleukin-6 induces vascular dysfunction and vascular and systemic inflammation
Knopp T, Jung R, Wild J, … Bochenek ML … Karbach S · European Heart Journal Open · 10.1093/ehjopen/oeae046
Endothelial PTP1B Deletion Promotes VWF Exocytosis and Venous Thromboinflammation
Zifkos K, Bochenek ML, Gogiraju R, … Schäfer K · Circulation Research · 10.1161/CIRCRESAHA.124.324214
Endothelial overexpression of transforming growth factor beta-induced (BIGH3) impairs venous thrombus resolution: possible role in CTEPH First author
Bochenek ML, Saar K, Nazari-Jahantigh M, … Schäfer K · JACC: Basic to Translational Science · 10.1016/j.jacbts.2023.08.005
Deletion of endothelial leptin receptors in mice promotes diet-induced obesity
Gogiraju R, Witzler C, Shahneh F, … Bochenek ML … Schäfer K · Scientific Reports · 10.1038/s41598-023-35281-7
Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation
Wittig J, Drekolia MK, Kyselova A, … Bochenek ML … Bibli SI · Redox Biology · 10.1016/j.redox.2023.102694
Arginase-1 deletion in erythrocytes promotes vascular calcification via enhanced GSNOR (S-Nitrosoglutathione Reductase) expression and NO signalling in smooth muscle cells
Gogiraju R, Renner L, Bochenek ML, … Schäfer K · Arteriosclerosis, Thrombosis, and Vascular Biology · 10.1161/ATVBAHA.122.318338
EPCR-PAR1 biased signalling regulates perfusion recovery and neovascularization in peripheral ischemia First author
Bochenek ML, Gogiraju R, Großmann S, … Schäfer K · JCI Insight · 10.1172/jci.insight.157701
Protein Tyrosine Phosphatase 1B deficiency in vascular smooth muscle cells promotes perivascular fibrosis following arterial injury
Gogiraju R*, Gachkar S*, Velmeden D*, … Bochenek ML … Schäfer K · Thrombosis and Haemostasis · 10.1055/s-0042-1755329
Tubulin-folding cofactor E deficiency promotes vascular dysfunction by increased endoplasmic reticulum stress
Efentakis P, Molitor M, Kossmann S, … Bochenek ML … Wenzel P · European Heart Journal · 10.1093/eurheartj/ehab222
Role of angiopoietin-2 in venous thrombus resolution and chronic thromboembolic disease
Hobohm L, Kölmel S, Niemann C, … Bochenek ML … Lankeit M · European Respiratory Journal · 10.1183/13993003.04196-2020
Brain-derived neurotrophic factor expression and signaling in different perivascular adipose tissue depots of patients with coronary artery disease
Zierold S, Buschmann K, Gachkar S, … Bochenek ML … Schäfer K · Journal of the American Heart Association · 10.1161/JAHA.120.018322
Age-dependent and –independent effects of perivascular adipose tissue and its paracrine activities during neointima formation
Schütz E*, Gogiraju R*, Pavlaki M, … Bochenek ML … Schäfer K · International Journal of Medical Sciences · 10.7150/ijms.37675
Activated endothelial TGFβ1 signaling promotes venous thrombus non-resolution in mice via endothelin-1: potential role for chronic thromboembolic pulmonary hypertension First author
Bochenek ML, Leidinger C, Rosinus NS, … Schäfer K · Circulation Research · 10.1161/CIRCRESAHA.119.315259
Increased lymphangiogenesis and lymphangiogenic growth factor expression in perivascular adipose tissue of patients with coronary artery disease
Drosos I, Pavlaki M, Ortega Carrillo MDP, … Bochenek ML … Schäfer K · Journal of Clinical Medicine · 10.3390/jcm8071000
Potential involvement of Osteopontin in inflammatory and fibrotic processes in Pulmonary Embolism and Chronic Thromboembolic Pulmonary Hypertension
Kölmel S, Hobohm L, Käberich A, … Bochenek ML … Lankeit M · Thrombosis and Haemostasis · 10.1055/s-0039-1692174
Angiogenic Endothelial Cell Signaling in Cardiac Hypertrophy and Heart Failure
Gogiraju R, Bochenek ML, Schäfer K · Frontiers in Cardiovascular Medicine · 10.3389/fcvm.2019.00020
Role of Endothelial Cells in Acute and Chronic Thrombosis First author
Bochenek ML, Schäfer K · Hämostaseologie · 10.1055/s-0038-1675614
Pulmonary arterial hypertension and endothelial dysfunction is linked to NADPH Oxidase-derived superoxide formation in venous thrombosis and pulmonary embolism in mice
Brandt M, Giokoglu E, Garlapati V, … Bochenek ML … Wenzel P · Oxidative Medicine and Cellular Longevity · 10.1155/2018/1860513
Endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice First author
Bochenek ML*, Bauer T*, Gogiraju R, … Schäfer K · Blood Advances · 10.1182/bloodadvances.2017014050
Endothelial Protein Tyrosine Phosphatase-1B knockdown enhances neointima formation in mice with diet-induced obesity
Jäger M*, Hubert A*, Gogiraju R, Bochenek ML, Münzel T, Schäfer K · Antioxidants & Redox Signaling · 10.1089/ars.2017.7169
Selective Deletion of Leptin Signaling in Endothelial Cells Enhances Neointima Formation and Phenocopies the Vascular Effects of Diet-Induced Obesity in Mice
Hubert A, Bochenek ML, Schütz E, Gogiraju R, Münzel T, Schäfer K · Arteriosclerosis, Thrombosis, and Vascular Biology · 10.1161/ATVBAHA.117.309798
Inorganic polyphosphate and Interferon lambda1/IL-29 are novel partners in the regulation of neutrophil-driven thromboinflammation
Chrysanthopoulou A, Kambas K, Stakos D, … Bochenek ML … Ritis K · The Journal of Pathology · 10.1002/path.4935
Absence of Transforming Growth Factor beta 1 in Murine Platelets Reduces Neointima Formation without Affecting Thrombosis
Schütz E, Bochenek ML, Riehl DR, … Schäfer K · Thrombosis and Haemostasis · 10.1160/TH17-02-0112
From thrombosis to fibrosis in Chronic Thromboembolic Pulmonary Hypertension First author
Bochenek ML, Rosinus NS, Lankeit M, … Schäfer K · Thrombosis and Haemostasis · 10.1160/TH16-10-0790
Endothelial cell senescence and thrombosis: ageing clots First author
Bochenek ML, Schütz E, Schäfer K · Thrombosis Research · 10.1016/j.thromres.2016.09.019
Endothelial deletion of protein tyrosine phosphatase-1B protect against pressure overload-induced heart failure in mice
Gogiraju R, Schroeter MR, Bochenek ML, … Schäfer K · Cardiovascular Research · 10.1093/cvr/cvw101
C3G/Rapgef1 is required in multipolar neurons for the transition to a bipolar morphology during cortical development
Shah B, Lutter D, Bochenek ML, … Püschel AW · PLOS ONE · 10.1371/journal.pone.0154174
Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice
Gogiraju R, Xu X, Bochenek ML, … Schäfer K · Journal of the American Heart Association · 10.1161/JAHA.115.001770
Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis
Wang Y*, Nakayama M*, Pitulescu M*, … Bochenek ML … Adams RH · Nature
Ephrin-B2 regulates endothelial cell morphology and motility independently of EPH-receptor binding First author
Bochenek ML, Dickinson S, Astin JW, Adams RH, Nobes CD · Journal of Cell Science
* shared first authorship
Full list: PubMed
Peer reviewer since 2018 for Thrombosis Research, Thrombosis and Haemostasis, Antioxidants & Redox Signaling, Oxidative Medicine and Cellular Longevity and Atherosclerosis.